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KDM5 Interacts with Foxo to Modulate Cellular Levels of Oxidative Stress
Increased cellular levels of oxidative stress are implicated in a large number of human diseases. Here we describe the transcription co-factor KDM5 (also known as Lid) as a new critical regulator of cellular redox state. Moreover, this occurs through a novel KDM5 activity whereby it alters the abili...
Autores principales: | , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2014
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4199495/ https://www.ncbi.nlm.nih.gov/pubmed/25329053 http://dx.doi.org/10.1371/journal.pgen.1004676 |