Cargando…

KDM5 Interacts with Foxo to Modulate Cellular Levels of Oxidative Stress

Increased cellular levels of oxidative stress are implicated in a large number of human diseases. Here we describe the transcription co-factor KDM5 (also known as Lid) as a new critical regulator of cellular redox state. Moreover, this occurs through a novel KDM5 activity whereby it alters the abili...

Descripción completa

Detalles Bibliográficos
Autores principales: Liu, Xingyin, Greer, Christina, Secombe, Julie
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4199495/
https://www.ncbi.nlm.nih.gov/pubmed/25329053
http://dx.doi.org/10.1371/journal.pgen.1004676