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Hsp40s Specify Functions of Hsp104 and Hsp90 Protein Chaperone Machines

Hsp100 family chaperones of microorganisms and plants cooperate with the Hsp70/Hsp40/NEF system to resolubilize and reactivate stress-denatured proteins. In yeast this machinery also promotes propagation of prions by fragmenting prion polymers. We previously showed the bacterial Hsp100 machinery coo...

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Detalles Bibliográficos
Autores principales: Reidy, Michael, Sharma, Ruchika, Shastry, Shankar, Roberts, Brittany-Lee, Albino-Flores, Ivan, Wickner, Sue, Masison, Daniel C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4199505/
https://www.ncbi.nlm.nih.gov/pubmed/25329162
http://dx.doi.org/10.1371/journal.pgen.1004720