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ssb Gene Duplication Restores the Viability of ΔholC and ΔholD Escherichia coli Mutants

The HolC-HolD (χψ) complex is part of the DNA polymerase III holoenzyme (Pol III HE) clamp-loader. Several lines of evidence indicate that both leading- and lagging-strand synthesis are affected in the absence of this complex. The Escherichia coli ΔholD mutant grows poorly and suppressor mutations t...

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Detalles Bibliográficos
Autores principales: Duigou, Stéphane, Silvain, Maud, Viguera, Enrique, Michel, Bénédicte
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4199511/
https://www.ncbi.nlm.nih.gov/pubmed/25329071
http://dx.doi.org/10.1371/journal.pgen.1004719