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ssb Gene Duplication Restores the Viability of ΔholC and ΔholD Escherichia coli Mutants
The HolC-HolD (χψ) complex is part of the DNA polymerase III holoenzyme (Pol III HE) clamp-loader. Several lines of evidence indicate that both leading- and lagging-strand synthesis are affected in the absence of this complex. The Escherichia coli ΔholD mutant grows poorly and suppressor mutations t...
| Autores principales: | , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Public Library of Science
2014
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4199511/ https://www.ncbi.nlm.nih.gov/pubmed/25329071 http://dx.doi.org/10.1371/journal.pgen.1004719 |