Targeting Apoptosis Signalling Kinase-1 (ASK-1) Does Not Prevent the Development of Neuropathy in Streptozotocin-Induced Diabetic Mice

Apoptosis signal-regulating kinase-1 (ASK1) is a mitogen-activated protein 3 kinase (MAPKKK/MAP3K) which lies upstream of the stress-activated MAPKs, JNK and p38. ASK1 may be activated by a variety of extracellular and intracellular stimuli. MAP kinase activation in the sensory nervous system as a r...

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Detalles Bibliográficos
Autores principales: Newton, Victoria L., Ali, Sumia, Duddy, Graham, Whitmarsh, Alan J., Gardiner, Natalie J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4199525/
https://www.ncbi.nlm.nih.gov/pubmed/25329046
http://dx.doi.org/10.1371/journal.pone.0107437

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4199525/
https://www.ncbi.nlm.nih.gov/pubmed/25329046
http://dx.doi.org/10.1371/journal.pone.0107437

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