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Matrix metalloproteinase-2 is downregulated in sciatic nerve by streptozotocin induced diabetes and/or treatment with minocycline: Implications for nerve regeneration

Minocycline is an inhibitor of matrix metalloproteinases (MMPs) and has been shown to have analgesic effects. Whilst increased expression of MMPs is associated with neuropathic pain, MMPs also play crucial roles in Wallerian degeneration and nerve regeneration. In this study we examined the expressi...

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Detalles Bibliográficos
Autores principales: Ali, Sumia, Driscoll, Heather E., Newton, Victoria L., Gardiner, Natalie J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Academic Press 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4199570/
https://www.ncbi.nlm.nih.gov/pubmed/25158309
http://dx.doi.org/10.1016/j.expneurol.2014.08.017