An AGEF-1/Arf GTPase/AP-1 Ensemble Antagonizes LET-23 EGFR Basolateral Localization and Signaling during C. elegans Vulva Induction

LET-23 Epidermal Growth Factor Receptor (EGFR) signaling specifies the vulval cell fates during C. elegans larval development. LET-23 EGFR localization on the basolateral membrane of the vulval precursor cells (VPCs) is required to engage the LIN-3 EGF-like inductive signal. The LIN-2 Cask/LIN-7 Vel...

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Detalles Bibliográficos
Autores principales: Skorobogata, Olga, Escobar-Restrepo, Juan M., Rocheleau, Christian E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4199573/
https://www.ncbi.nlm.nih.gov/pubmed/25329472
http://dx.doi.org/10.1371/journal.pgen.1004728

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4199573/
https://www.ncbi.nlm.nih.gov/pubmed/25329472
http://dx.doi.org/10.1371/journal.pgen.1004728

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