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Pioglitazone Improves Fat Distribution, the Adipokine Profile and Hepatic Insulin Sensitivity in Non-Diabetic End-Stage Renal Disease Subjects on Maintenance Dialysis: A Randomized Cross-Over Pilot Study

BACKGROUND: Fat redistribution, increased inflammation and insulin resistance are prevalent in non-diabetic subjects treated with maintenance dialysis. The aim of this study was to test whether pioglitazone, a powerful insulin sensitizer, alters body fat distribution and adipokine secretion in these...

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Detalles Bibliográficos
Autores principales: Zanchi, Anne, Tappy, Luc, Lê, Kim-Anne, Bortolotti, Murielle, Theumann, Nicolas, Halabi, Georges, Gauthier, Thierry, Mathieu, Claudine, Tremblay, Sylvie, Bertrand, Pauline Coti, Burnier, Michel, Teta, Daniel
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4199598/
https://www.ncbi.nlm.nih.gov/pubmed/25330088
http://dx.doi.org/10.1371/journal.pone.0109134