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Pioglitazone Improves Fat Distribution, the Adipokine Profile and Hepatic Insulin Sensitivity in Non-Diabetic End-Stage Renal Disease Subjects on Maintenance Dialysis: A Randomized Cross-Over Pilot Study
BACKGROUND: Fat redistribution, increased inflammation and insulin resistance are prevalent in non-diabetic subjects treated with maintenance dialysis. The aim of this study was to test whether pioglitazone, a powerful insulin sensitizer, alters body fat distribution and adipokine secretion in these...
Autores principales: | Zanchi, Anne, Tappy, Luc, Lê, Kim-Anne, Bortolotti, Murielle, Theumann, Nicolas, Halabi, Georges, Gauthier, Thierry, Mathieu, Claudine, Tremblay, Sylvie, Bertrand, Pauline Coti, Burnier, Michel, Teta, Daniel |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2014
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4199598/ https://www.ncbi.nlm.nih.gov/pubmed/25330088 http://dx.doi.org/10.1371/journal.pone.0109134 |
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