Sequential Application of Ligand and Structure Based Modeling Approaches to Index Chemicals for Their hH(4)R Antagonism

The human histamine H(4) receptor (hH(4)R), a member of the G-protein coupled receptors (GPCR) family, is an increasingly attractive drug target. It plays a key role in many cell pathways and many hH(4)R ligands are studied for the treatment of several inflammatory, allergic and autoimmune disorders...

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Detalles Bibliográficos
Autores principales: Pappalardo, Matteo, Shachaf, Nir, Basile, Livia, Milardi, Danilo, Zeidan, Mouhammed, Raiyn, Jamal, Guccione, Salvatore, Rayan, Anwar
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4199621/
https://www.ncbi.nlm.nih.gov/pubmed/25330207
http://dx.doi.org/10.1371/journal.pone.0109340

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4199621/
https://www.ncbi.nlm.nih.gov/pubmed/25330207
http://dx.doi.org/10.1371/journal.pone.0109340

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