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Sequential Application of Ligand and Structure Based Modeling Approaches to Index Chemicals for Their hH(4)R Antagonism
The human histamine H(4) receptor (hH(4)R), a member of the G-protein coupled receptors (GPCR) family, is an increasingly attractive drug target. It plays a key role in many cell pathways and many hH(4)R ligands are studied for the treatment of several inflammatory, allergic and autoimmune disorders...
| Autores principales: | , , , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Public Library of Science
2014
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4199621/ https://www.ncbi.nlm.nih.gov/pubmed/25330207 http://dx.doi.org/10.1371/journal.pone.0109340 |