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PDE2 Is a Novel Target for Attenuating Tumor Formation in a Mouse Model of UVB-Induced Skin Carcinogenesis

Our previous studies demonstrated that the topical application of caffeine is a potent inhibitor of UVB-induced carcinogenesis and selectively increases apoptosis in tumors but not in non-tumor areas of the epidermis in mice that are at a high risk for developing skin cancer. While this effect is ma...

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Detalles Bibliográficos
Autores principales: Bernard, Jamie J., Lou, You-Rong, Peng, Qing-Yun, Li, Tao, Lu, Yao-Ping
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4199678/
https://www.ncbi.nlm.nih.gov/pubmed/25330380
http://dx.doi.org/10.1371/journal.pone.0109862