Deletion of Thioredoxin Interacting Protein (TXNIP) Augments Hyperoxia-Induced Vaso-Obliteration in a Mouse Model of Oxygen Induced-Retinopathy

We have recently shown that thioredoxin interacting protein (TXNIP) is required for VEGF-mediated VEGFR2 receptor activation and angiogenic signal. Retinas from TXNIP knockout mice (TKO) exhibited higher cellular antioxidant defense compared to wild type (WT). This study aimed to examine the impact...

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Detalles Bibliográficos
Autores principales: Abdelsaid, Mohammed A., Matragoon, Suraporn, Ergul, Adviye, El-Remessy, Azza B.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4199686/
https://www.ncbi.nlm.nih.gov/pubmed/25329456
http://dx.doi.org/10.1371/journal.pone.0110388

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4199686/
https://www.ncbi.nlm.nih.gov/pubmed/25329456
http://dx.doi.org/10.1371/journal.pone.0110388

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