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The Alternative Oxidase AOX Does Not Rescue the Phenotype of tko(25t) Mutant Flies

A point mutation [technical knockout(25t) (tko(25t))] in the Drosophila gene coding for mitoribosomal protein S12 generates a phenotype of developmental delay and bang sensitivity. tko(25t) has been intensively studied as an animal model for human mitochondrial diseases associated with deficiency of...

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Detalles Bibliográficos
Autores principales: Kemppainen, Kia K., Kemppainen, Esko, Jacobs, Howard T.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Genetics Society of America 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4199707/
https://www.ncbi.nlm.nih.gov/pubmed/25147191
http://dx.doi.org/10.1534/g3.114.013946