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The Alternative Oxidase AOX Does Not Rescue the Phenotype of tko(25t) Mutant Flies
A point mutation [technical knockout(25t) (tko(25t))] in the Drosophila gene coding for mitoribosomal protein S12 generates a phenotype of developmental delay and bang sensitivity. tko(25t) has been intensively studied as an animal model for human mitochondrial diseases associated with deficiency of...
Autores principales: | Kemppainen, Kia K., Kemppainen, Esko, Jacobs, Howard T. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Genetics Society of America
2014
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4199707/ https://www.ncbi.nlm.nih.gov/pubmed/25147191 http://dx.doi.org/10.1534/g3.114.013946 |
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