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Allele-Specific Induction of IL-1β Expression by C/EBPβ and PU.1 Contributes to Increased Tuberculosis Susceptibility

Mycobacterium tuberculosis infection is associated with a spectrum of clinical outcomes, from long-term latent infection to different manifestations of progressive disease. Pro-inflammatory pathways, such as those controlled by IL-1β, have the contrasting potential both to prevent disease by restric...

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Detalles Bibliográficos
Autores principales: Zhang, Guoliang, Zhou, Boping, Li, Shaoyuan, Yue, Jun, Yang, Hui, Wen, Yuxin, Zhan, Senlin, Wang, Wenfei, Liao, Mingfeng, Zhang, Mingxia, Zeng, Gucheng, Feng, Carl G., Sassetti, Christopher M., Chen, Xinchun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4199770/
https://www.ncbi.nlm.nih.gov/pubmed/25329476
http://dx.doi.org/10.1371/journal.ppat.1004426