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Allele-Specific Induction of IL-1β Expression by C/EBPβ and PU.1 Contributes to Increased Tuberculosis Susceptibility
Mycobacterium tuberculosis infection is associated with a spectrum of clinical outcomes, from long-term latent infection to different manifestations of progressive disease. Pro-inflammatory pathways, such as those controlled by IL-1β, have the contrasting potential both to prevent disease by restric...
Autores principales: | Zhang, Guoliang, Zhou, Boping, Li, Shaoyuan, Yue, Jun, Yang, Hui, Wen, Yuxin, Zhan, Senlin, Wang, Wenfei, Liao, Mingfeng, Zhang, Mingxia, Zeng, Gucheng, Feng, Carl G., Sassetti, Christopher M., Chen, Xinchun |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2014
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4199770/ https://www.ncbi.nlm.nih.gov/pubmed/25329476 http://dx.doi.org/10.1371/journal.ppat.1004426 |
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