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Human Cytomegalovirus Drives Epigenetic Imprinting of the IFNG Locus in NKG2C(hi) Natural Killer Cells

Memory type 1 T helper (T(H)1) cells are characterized by the stable expression of interferon (IFN)-γ as well as by the epigenetic imprinting of the IFNG locus. Among innate cells, NK cells play a crucial role in the defense against cytomegalovirus (CMV) and represent the main source of IFN-γ. Recen...

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Detalles Bibliográficos
Autores principales: Luetke-Eversloh, Merlin, Hammer, Quirin, Durek, Pawel, Nordström, Karl, Gasparoni, Gilles, Pink, Matthias, Hamann, Alf, Walter, Jörn, Chang, Hyun-Dong, Dong, Jun, Romagnani, Chiara
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4199780/
https://www.ncbi.nlm.nih.gov/pubmed/25329659
http://dx.doi.org/10.1371/journal.ppat.1004441