Epstein-Barr virus IL-10 gene expression by a recombinant murine gammaherpesvirus in vivo enhances acute pathogenicity but does not affect latency or reactivation

BACKGROUND: Many viral genes affect cytokine function within infected hosts, with interleukin 10 (IL-10) as a commonly targeted mediator. Epstein-Barr virus (EBV) encodes an IL-10 homologue (vIL-10) expressed during productive (lytic) infection and induces expression of cellular IL-10 (cIL-10) durin...

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Detalles Bibliográficos
Autores principales: Lindquester, Gary J, Greer, Kimberly A, Stewart, James P, Sample, Jeffery T
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2014
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4199788/
https://www.ncbi.nlm.nih.gov/pubmed/25324959
http://dx.doi.org/10.1186/2042-4280-5-1

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4199788/
https://www.ncbi.nlm.nih.gov/pubmed/25324959
http://dx.doi.org/10.1186/2042-4280-5-1

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