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Epstein-Barr virus IL-10 gene expression by a recombinant murine gammaherpesvirus in vivo enhances acute pathogenicity but does not affect latency or reactivation
BACKGROUND: Many viral genes affect cytokine function within infected hosts, with interleukin 10 (IL-10) as a commonly targeted mediator. Epstein-Barr virus (EBV) encodes an IL-10 homologue (vIL-10) expressed during productive (lytic) infection and induces expression of cellular IL-10 (cIL-10) durin...
Autores principales: | Lindquester, Gary J, Greer, Kimberly A, Stewart, James P, Sample, Jeffery T |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2014
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4199788/ https://www.ncbi.nlm.nih.gov/pubmed/25324959 http://dx.doi.org/10.1186/2042-4280-5-1 |
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