Secretion of IL-16 through TNFR1 and calpain-caspase signaling contributes to MRSA pneumonia

Staphylococcus aureus is a major cause of severe pneumonia. Multiple mechanisms of proinflammatory signaling are activated to recruit immune cells into the airway in response to S. aureus. We found that IL-16, a T cell cytokine that binds CD4, is potently activated by S. aureus, specifically by prot...

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Detalles Bibliográficos
Autores principales: Ahn, Danielle, Parker, Dane, Planet, Paul J., Nieto, Pamela A., Bueno, Susan M., Prince, Alice
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2014
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4199935/
https://www.ncbi.nlm.nih.gov/pubmed/24736233
http://dx.doi.org/10.1038/mi.2014.24

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4199935/
https://www.ncbi.nlm.nih.gov/pubmed/24736233
http://dx.doi.org/10.1038/mi.2014.24

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