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Secretion of IL-16 through TNFR1 and calpain-caspase signaling contributes to MRSA pneumonia
Staphylococcus aureus is a major cause of severe pneumonia. Multiple mechanisms of proinflammatory signaling are activated to recruit immune cells into the airway in response to S. aureus. We found that IL-16, a T cell cytokine that binds CD4, is potently activated by S. aureus, specifically by prot...
| Autores principales: | , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
2014
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4199935/ https://www.ncbi.nlm.nih.gov/pubmed/24736233 http://dx.doi.org/10.1038/mi.2014.24 |