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(R)-(+)-α-Lipoic acid protected NG108-15 cells against H(2)O(2)-induced cell death through PI3K-Akt/GSK-3β pathway and suppression of NF-κβ-cytokines
Alpha-lipoic acid, a potent antioxidant with multifarious pharmacological benefits has been reported to be neuroprotective in several neuronal models and used to treat neurological disorders such as Alzheimer’s disease. Nonetheless, conclusive mechanisms of alpha-lipoic acid for its protective effec...
Autores principales: | , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Dove Medical Press
2014
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4199983/ https://www.ncbi.nlm.nih.gov/pubmed/25336920 http://dx.doi.org/10.2147/DDDT.S67980 |