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(R)-(+)-α-Lipoic acid protected NG108-15 cells against H(2)O(2)-induced cell death through PI3K-Akt/GSK-3β pathway and suppression of NF-κβ-cytokines

Alpha-lipoic acid, a potent antioxidant with multifarious pharmacological benefits has been reported to be neuroprotective in several neuronal models and used to treat neurological disorders such as Alzheimer’s disease. Nonetheless, conclusive mechanisms of alpha-lipoic acid for its protective effec...

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Detalles Bibliográficos
Autores principales:	Kamarudin, Muhamad Noor Alfarizal, Mohd Raflee, Nur Afiqah, Syed Hussein, Sharifah Salwa, Lo, Jia Ye, Supriady, Hadi, Abdul Kadir, Habsah
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Dove Medical Press 2014
Materias:	Original Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4199983/ https://www.ncbi.nlm.nih.gov/pubmed/25336920 http://dx.doi.org/10.2147/DDDT.S67980

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