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Receptor interacting protein 140 attenuates endoplasmic reticulum stress in neurons and protects against cell death

Inositol 1, 4, 5-trisphosphate receptor (IP(3)R)-mediated Ca(2+) release from the endoplasmic reticulum (ER) triggers many physiological responses in neurons and when uncontrolled can cause ER stress that contributes to neurological disease. Here we show that the unfolded protein response (UPR) in n...

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Detalles Bibliográficos
Autores principales: Feng, Xudong, Krogh, Kelly A., Wu, Cheng-Ying, Lin, Yi-Wei, Tsai, Hong-Chieh, Thayer, Stanley A., Wei, Li-Na
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4200015/
https://www.ncbi.nlm.nih.gov/pubmed/25066731
http://dx.doi.org/10.1038/ncomms5487