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Factorial design applied to the optimization of lipid composition of topical antiherpetic nanoemulsions containing isoflavone genistein

The aim of this study was to optimize topical nanoemulsions containing genistein, by means of a 23 full factorial design based on physicochemical properties and skin retention. The experimental arrangement was constructed using oil type (isopropyl myristate or castor oil), phospholipid type (distear...

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Detalles Bibliográficos
Autores principales: Argenta, Débora Fretes, de Mattos, Cristiane Bastos, Misturini, Fabíola Dallarosa, Koester, Leticia Scherer, Bassani, Valquiria Linck, Simões, Cláudia Maria Oliveira, Teixeira, Helder Ferreira
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove Medical Press 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4200020/
https://www.ncbi.nlm.nih.gov/pubmed/25336951
http://dx.doi.org/10.2147/IJN.S67732