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Factorial design applied to the optimization of lipid composition of topical antiherpetic nanoemulsions containing isoflavone genistein
The aim of this study was to optimize topical nanoemulsions containing genistein, by means of a 23 full factorial design based on physicochemical properties and skin retention. The experimental arrangement was constructed using oil type (isopropyl myristate or castor oil), phospholipid type (distear...
Autores principales: | Argenta, Débora Fretes, de Mattos, Cristiane Bastos, Misturini, Fabíola Dallarosa, Koester, Leticia Scherer, Bassani, Valquiria Linck, Simões, Cláudia Maria Oliveira, Teixeira, Helder Ferreira |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Dove Medical Press
2014
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4200020/ https://www.ncbi.nlm.nih.gov/pubmed/25336951 http://dx.doi.org/10.2147/IJN.S67732 |
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