Translation of genomics-guided RNA-based personalised cancer vaccines: towards the bedside

Cancer is a disease caused by DNA mutations. Cancer therapies targeting defined functional mutations have shown clinical benefit. However, as 95% of the mutations in a tumour are unique to that single patient and only a small number of mutations are shared between patients, the addressed medical nee...

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Detalles Bibliográficos
Autores principales: Boisguérin, V, Castle, J C, Loewer, M, Diekmann, J, Mueller, F, Britten, C M, Kreiter, S, Türeci, Ö, Sahin, U
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2014
Materias:
Minireview
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4200076/
https://www.ncbi.nlm.nih.gov/pubmed/25314223
http://dx.doi.org/10.1038/bjc.2013.820

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4200076/
https://www.ncbi.nlm.nih.gov/pubmed/25314223
http://dx.doi.org/10.1038/bjc.2013.820

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