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Translation of genomics-guided RNA-based personalised cancer vaccines: towards the bedside
Cancer is a disease caused by DNA mutations. Cancer therapies targeting defined functional mutations have shown clinical benefit. However, as 95% of the mutations in a tumour are unique to that single patient and only a small number of mutations are shared between patients, the addressed medical nee...
Autores principales: | Boisguérin, V, Castle, J C, Loewer, M, Diekmann, J, Mueller, F, Britten, C M, Kreiter, S, Türeci, Ö, Sahin, U |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group
2014
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4200076/ https://www.ncbi.nlm.nih.gov/pubmed/25314223 http://dx.doi.org/10.1038/bjc.2013.820 |
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