BRAF(V600E) melanoma cells secrete factors that activate stromal fibroblasts and enhance tumourigenicity

BACKGROUND: Melanoma, the most lethal form of skin cancer, is responsible for over 80% of all skin cancer deaths and is highly metastatic, readily spreading to the lymph nodes or metastasising to other organs. The frequent genetic mutation found in metastatic melanoma, BRAF(V600E), results in consti...

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Detalles Bibliográficos
Autores principales: Whipple, C A, Brinckerhoff, C E
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2014
Materias:
Molecular Diagnostics
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4200092/
https://www.ncbi.nlm.nih.gov/pubmed/25117819
http://dx.doi.org/10.1038/bjc.2014.452

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4200092/
https://www.ncbi.nlm.nih.gov/pubmed/25117819
http://dx.doi.org/10.1038/bjc.2014.452

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