Cargando…
BRAF(V600E) melanoma cells secrete factors that activate stromal fibroblasts and enhance tumourigenicity
BACKGROUND: Melanoma, the most lethal form of skin cancer, is responsible for over 80% of all skin cancer deaths and is highly metastatic, readily spreading to the lymph nodes or metastasising to other organs. The frequent genetic mutation found in metastatic melanoma, BRAF(V600E), results in consti...
| Autores principales: | , |
|---|---|
| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Nature Publishing Group
2014
|
| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4200092/ https://www.ncbi.nlm.nih.gov/pubmed/25117819 http://dx.doi.org/10.1038/bjc.2014.452 |