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Expression and DNA methylation of TNF, IFNG and FOXP3 in colorectal cancer and their prognostic significance

BACKGROUND: Colorectal cancer (CRC) progression is associated with suppression of host cell-mediated immunity and local immune escape mechanisms. Our aim was to assess the immune function in terms of expression of TNF, IFNG and FOXP3 in CRC. METHODS: Sixty patients with CRC and 15 matched controls w...

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Detalles Bibliográficos
Autores principales: Ganapathi, S K, Beggs, A D, Hodgson, S V, Kumar, D
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4200101/
https://www.ncbi.nlm.nih.gov/pubmed/25225903
http://dx.doi.org/10.1038/bjc.2014.477