Anti-proliferative but not anti-angiogenic tyrosine kinase inhibitors enrich for cancer stem cells in soft tissue sarcoma

BACKGROUND: Increasing studies implicate cancer stem cells (CSCs) as the source of resistance and relapse following conventional cytotoxic therapies. Few studies have examined the response of CSCs to targeted therapies, such as tyrosine kinase inhibitors (TKIs). We hypothesized that TKIs would have...

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Detalles Bibliográficos
Autores principales: Canter, Robert J, Ames, Erik, Mac, Stephanie, Grossenbacher, Steven K, Chen, Mingyi, Li, Chin-Shang, Borys, Dariusz, Smith, Rachel C, Tellez, Joe, Sayers, Thomas J, Monjazeb, Arta M, Murphy, William J
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2014
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4200119/
https://www.ncbi.nlm.nih.gov/pubmed/25301268
http://dx.doi.org/10.1186/1471-2407-14-756

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4200119/
https://www.ncbi.nlm.nih.gov/pubmed/25301268
http://dx.doi.org/10.1186/1471-2407-14-756

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