Activation of C6 glioblastoma cell ceruloplasmin expression by neighboring human brain endothelia-derived interleukins in an in vitro blood–brain barrier model system

BACKGROUND: Iron transport across the blood–brain barrier (BBB) involves the cooperation of brain microvascular endothelial cells (BMVEC) and their neighboring astrocytes. Astrocytes secrete a soluble form of ceruloplasmin (sCp) which, in turn, acts to export iron from ferroportin (Fpn) on the basol...

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Detalles Bibliográficos
Autores principales: McCarthy, Ryan C, Kosman, Daniel J
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2014
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4200123/
https://www.ncbi.nlm.nih.gov/pubmed/25311416
http://dx.doi.org/10.1186/s12964-014-0065-7

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4200123/
https://www.ncbi.nlm.nih.gov/pubmed/25311416
http://dx.doi.org/10.1186/s12964-014-0065-7

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