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The roles of mitoferrin-2 in the process of arsenic trioxide-induced cell damage in human gliomas

BACKGROUND: Among glioma treatment strategies, arsenic trioxide (As(2)O(3)) has shown efficacy as a therapeutic agent against human gliomas. However, the exact antitumor mechanism of action of As(2)O(3) is still unclear. Mitochondria are considered to be the major source of intracellular reactive ox...

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Detalles Bibliográficos
Autores principales: Wang, Chunlei, Chen, Xiaofeng, Zou, Huichao, Chen, Xin, Liu, Yaohua, Zhao, Shiguang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4200193/
https://www.ncbi.nlm.nih.gov/pubmed/25256833
http://dx.doi.org/10.1186/s40001-014-0049-5