Selective inhibitors of nuclear export (SINE)– a novel class of anti-cancer agents

Dysregulation of the nucleo-cytoplasmic transport of proteins plays an important role in carcinogenesis. The nuclear export of proteins depends on the activity of transport proteins, exportins. Exportins belong to the karyopherin β superfamily. Exportin-1 (XPO1), also known as chromosomal region mai...

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Detalles Bibliográficos
Autores principales: Parikh, Kaushal, Cang, Shundong, Sekhri, Arunabh, Liu, Delong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2014
Materias:
Review
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4200201/
https://www.ncbi.nlm.nih.gov/pubmed/25316614
http://dx.doi.org/10.1186/s13045-014-0078-0

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4200201/
https://www.ncbi.nlm.nih.gov/pubmed/25316614
http://dx.doi.org/10.1186/s13045-014-0078-0

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