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A Cytosolic Relay of Heat Shock Proteins HSP70-1A and HSP90β Monitors the Folding Trajectory of the Serotonin Transporter

Mutations in the C terminus of the serotonin transporter (SERT) disrupt folding and export from the endoplasmic reticulum. Here we examined the hypothesis that a cytosolic heat shock protein relay was recruited to the C terminus to assist folding of SERT. This conjecture was verified by the followin...

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Detalles Bibliográficos
Autores principales: El-Kasaby, Ali, Koban, Florian, Sitte, Harald H., Freissmuth, Michael, Sucic, Sonja
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Biochemistry and Molecular Biology 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4200255/
https://www.ncbi.nlm.nih.gov/pubmed/25202009
http://dx.doi.org/10.1074/jbc.M114.595090