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The sodium channel β1 subunit mediates outgrowth of neurite-like processes on breast cancer cells and promotes tumour growth and metastasis

Voltage-gated Na(+) channels (VGSCs) are heteromeric proteins composed of pore-forming α subunits and smaller β subunits. The β subunits are multifunctional channel modulators and are members of the immunoglobulin superfamily of cell adhesion molecules (CAMs). β1, encoded by SCN1B, is best character...

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Detalles Bibliográficos
Autores principales: Nelson, Michaela, Millican-Slater, Rebecca, Forrest, Lorna C, Brackenbury, William J
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Blackwell Publishing Ltd 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4200311/
https://www.ncbi.nlm.nih.gov/pubmed/24729314
http://dx.doi.org/10.1002/ijc.28890