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In vitro and in vivo characterization of a West Nile virus MAD78 infectious clone

The viral determinants governing the varied neuropathogenicity of different West Nile virus (WNV) strains are poorly understood. Here, we generated an infectious clone (WNV-MAD(IC)) of the non-pathogenic strain WNV-MAD78 and compared its replication to that of parental WNV-MAD78 and a WNV-MAD78 infe...

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Detalles Bibliográficos
Autores principales: Hussmann, Katherine L., Vandergaast, Rianna, Ochsner, Susan Park, Huang, Albert C., Gale, Michael, Fredericksen, Brenda L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Vienna 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4200346/
https://www.ncbi.nlm.nih.gov/pubmed/25023336
http://dx.doi.org/10.1007/s00705-014-2176-2