A novel crosstalk between BRCA1 and sirtuin 1 in ovarian cancer

BRCA mutations are the main known hereditary factors for ovarian cancer. Notably, emerging evidence has led to considerable interest in the role of sirtuin 1 (SIRT1) in ovarian cancer development. However, dynamic crosstalk between BRCA1 and SIRT1 is poorly understood. Here, we showed that: (i) BRCA...

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Detalles Bibliográficos
Autores principales: Li, Da, Bi, Fang-Fang, Chen, Na-Na, Cao, Ji-Min, Sun, Wu-Ping, Zhou, Yi-Ming, Li, Chun-Yan, Yang, Qing
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2014
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4200400/
https://www.ncbi.nlm.nih.gov/pubmed/25323003
http://dx.doi.org/10.1038/srep06666

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4200400/
https://www.ncbi.nlm.nih.gov/pubmed/25323003
http://dx.doi.org/10.1038/srep06666

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