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SMG1 Acts as a Novel Potential Tumor Suppressor with Epigenetic Inactivation in Acute Myeloid Leukemia

Suppressor with morphogenetic effect on genitalia family member (SMG1) belongs to a family of phosphoinositide 3-kinase-related kinases and is the main kinase involved in nonsense-mediated mRNA decay. Recently, SMG1 was suggested as a novel potential tumor suppressor gene, particularly in hypoxic tu...

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Detalles Bibliográficos
Autores principales: Du, Yahui, Lu, Fei, Li, Peng, Ye, Jingjing, Ji, Min, Ma, Daoxin, Ji, Chunyan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4200422/
https://www.ncbi.nlm.nih.gov/pubmed/25257528
http://dx.doi.org/10.3390/ijms150917065