Leptin Induces Oncostatin M Production in Osteoblasts by Downregulating miR-93 through the Akt Signaling Pathway

Inflammatory response and articular destruction are common symptoms of osteoarthritis (OA) and rheumatoid arthritis (RA). Leptin, an adipocyte-secreted hormone that centrally regulates weight control, may exert proinflammatory effects in the joint, depending on the immune response. Yet, the mechanis...

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Detalles Bibliográficos
Autores principales: Yang, Wei-Hung, Tsai, Chun-Hao, Fong, Yi-Chin, Huang, Yuan-Li, Wang, Shoou-Jyi, Chang, Yung-Sen, Tang, Chih-Hsin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2014
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4200751/
https://www.ncbi.nlm.nih.gov/pubmed/25198901
http://dx.doi.org/10.3390/ijms150915778

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4200751/
https://www.ncbi.nlm.nih.gov/pubmed/25198901
http://dx.doi.org/10.3390/ijms150915778

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