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Leptin Induces Oncostatin M Production in Osteoblasts by Downregulating miR-93 through the Akt Signaling Pathway

Inflammatory response and articular destruction are common symptoms of osteoarthritis (OA) and rheumatoid arthritis (RA). Leptin, an adipocyte-secreted hormone that centrally regulates weight control, may exert proinflammatory effects in the joint, depending on the immune response. Yet, the mechanis...

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Detalles Bibliográficos
Autores principales:	Yang, Wei-Hung, Tsai, Chun-Hao, Fong, Yi-Chin, Huang, Yuan-Li, Wang, Shoou-Jyi, Chang, Yung-Sen, Tang, Chih-Hsin
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2014
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4200751/ https://www.ncbi.nlm.nih.gov/pubmed/25198901 http://dx.doi.org/10.3390/ijms150915778

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