Inhibition of Autophagy via Activation of PI3K/Akt Pathway Contributes to the Protection of Ginsenoside Rb1 against Neuronal Death Caused by Ischemic Insults

Lethal autophagy is a pathway leading to neuronal death caused by transient global ischemia. In this study, we examined the effect of Ginsenoside Rb1 (GRb1) on ischemia/reperfusion-induced autophagic neuronal death and investigated the role of PI3K/Akt. Ischemic neuronal death in vitro was induced b...

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Detalles Bibliográficos
Autores principales: Luo, Tianfei, Liu, Guiying, Ma, Hongxi, Lu, Bin, Xu, Haiyang, Wang, Yujing, Wu, Jiang, Ge, Pengfei, Liang, Jianmin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2014
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4200757/
https://www.ncbi.nlm.nih.gov/pubmed/25257523
http://dx.doi.org/10.3390/ijms150915426

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4200757/
https://www.ncbi.nlm.nih.gov/pubmed/25257523
http://dx.doi.org/10.3390/ijms150915426

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