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Inhibition of Autophagy via Activation of PI3K/Akt Pathway Contributes to the Protection of Ginsenoside Rb1 against Neuronal Death Caused by Ischemic Insults
Lethal autophagy is a pathway leading to neuronal death caused by transient global ischemia. In this study, we examined the effect of Ginsenoside Rb1 (GRb1) on ischemia/reperfusion-induced autophagic neuronal death and investigated the role of PI3K/Akt. Ischemic neuronal death in vitro was induced b...
Autores principales: | Luo, Tianfei, Liu, Guiying, Ma, Hongxi, Lu, Bin, Xu, Haiyang, Wang, Yujing, Wu, Jiang, Ge, Pengfei, Liang, Jianmin |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2014
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4200757/ https://www.ncbi.nlm.nih.gov/pubmed/25257523 http://dx.doi.org/10.3390/ijms150915426 |
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