High-Dose Diosgenin Reduces Bone Loss in Ovariectomized Rats via Attenuation of the RANKL/OPG Ratio

The aim of this study was to evaluate effect of diosgenin (DG) on rats that had osteoporosis-like features induced by ovariectomy (OVX). Seventy-two six-month-old female Wistar rats were subjected to either ovariectomy (n = 60) or Sham operation (SHAM group, n = 12). Beginning at one week post-ovari...

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Detalles Bibliográficos
Autores principales: Zhang, Zhiguo, Song, Changheng, Fu, Xiaowei, Liu, Meijie, Li, Yan, Pan, Jinghua, Liu, Hong, Wang, Shaojun, Xiang, Lihua, Xiao, Gary Guishan, Ju, Dahong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2014
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4200779/
https://www.ncbi.nlm.nih.gov/pubmed/25257532
http://dx.doi.org/10.3390/ijms150917130

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4200779/
https://www.ncbi.nlm.nih.gov/pubmed/25257532
http://dx.doi.org/10.3390/ijms150917130

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