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High-Dose Diosgenin Reduces Bone Loss in Ovariectomized Rats via Attenuation of the RANKL/OPG Ratio
The aim of this study was to evaluate effect of diosgenin (DG) on rats that had osteoporosis-like features induced by ovariectomy (OVX). Seventy-two six-month-old female Wistar rats were subjected to either ovariectomy (n = 60) or Sham operation (SHAM group, n = 12). Beginning at one week post-ovari...
Autores principales: | Zhang, Zhiguo, Song, Changheng, Fu, Xiaowei, Liu, Meijie, Li, Yan, Pan, Jinghua, Liu, Hong, Wang, Shaojun, Xiang, Lihua, Xiao, Gary Guishan, Ju, Dahong |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2014
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4200779/ https://www.ncbi.nlm.nih.gov/pubmed/25257532 http://dx.doi.org/10.3390/ijms150917130 |
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