The DNA Repair Enzyme Apurinic/Apyrimidinic Endonuclease (Apex Nuclease) 2 Has the Potential to Protect against Down-Regulation of Chondrocyte Activity in Osteoarthritis

Apurinic/apyrimidinic endonuclease 2 (Apex 2) plays a critical role in DNA repair caused by oxidative damage in a variety of human somatic cells. We speculated that chondrocyte Apex 2 may protect against the catabolic process of articular cartilage in osteoarthritis (OA). Higher levels of Apex 2 exp...

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Detalles Bibliográficos
Autores principales: Yui, Naoko, Yoshioka, Hirotaka, Fujiya, Hiroto, Musha, Haruki, Beppu, Moroe, Karasawa, Rie, Yudoh, Kazuo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2014
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4200784/
https://www.ncbi.nlm.nih.gov/pubmed/25158232
http://dx.doi.org/10.3390/ijms150914921

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4200784/
https://www.ncbi.nlm.nih.gov/pubmed/25158232
http://dx.doi.org/10.3390/ijms150914921

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