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Comprehensive Luciferase-Based Reporter Gene Assay Reveals Previously Masked Up-Regulatory Effects of miRNAs
MicroRNAs (miRNAs) are small non-coding RNAs that regulate the majority of the transcriptome at a post-transcriptional level. Because of this critical role, it is important to ensure that the assays used to determine their functionality are robust and reproducible. Typically, the reporter gene assay...
Autores principales: | Campos-Melo, Danae, Droppelmann, Cristian A., Volkening, Kathryn, Strong, Michael J. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2014
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4200788/ https://www.ncbi.nlm.nih.gov/pubmed/25192285 http://dx.doi.org/10.3390/ijms150915592 |
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