Curcumin Promotes KLF5 Proteasome Degradation through Downregulating YAP/TAZ in Bladder Cancer Cells

KLF5 (Krüppel-like factor 5) plays critical roles in normal and cancer cell proliferation through modulating cell cycle progression. In this study, we demonstrated that curcumin targeted KLF5 by promoting its proteasome degradation, but not by inhibiting its transcription in bladder cancer cells. We...

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Detalles Bibliográficos
Autores principales: Gao, Yang, Shi, Qi, Xu, Shan, Du, Chong, Liang, Liang, Wu, Kaijie, Wang, Ke, Wang, Xinyang, Chang, Luke S., He, Dalin, Guo, Peng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2014
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4200832/
https://www.ncbi.nlm.nih.gov/pubmed/25170806
http://dx.doi.org/10.3390/ijms150915173

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4200832/
https://www.ncbi.nlm.nih.gov/pubmed/25170806
http://dx.doi.org/10.3390/ijms150915173

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